Duties Responsibilities Laboratory Sample Processing: Prepare biological and environmental samples for metabolomics analysis. Perform metabolite extractions from tissues, cells, plasma, serum, urine, microbial cultures, plant materials, and other complex sample matrices. Prepare calibration standards, internal standards, blanks, and quality control samples. Perform sample concentration, cleanup, and purification procedures as needed, including solvent evaporation and solid-phase extraction techniques. Organize and prepare analytical sample batches for LC-MS/MS analysis. LC-MS/MS Analysis: Operate LC-MS/MS instrumentation for targeted and untargeted metabolomics analyses. Prepare analytical sequences and verify instrument readiness prior to sample analysis. Monitor instrument performance and analytical quality during project execution. Assist with routine instrument maintenance, calibration, and troubleshooting. Review quality control samples and analytical performance metrics to ensure data quality. Facility Operations: Maintain laboratory supplies, reagents, and consumables. Maintain required laboratory safety training and adhere to university safety policies and procedures. Contribute to maintaining a safe, clean, organized, and efficient laboratory environment. Project Support: Work closely with senior scientific staff to implement analytical approaches appropriate for individual projects. Adjust extraction procedures, dilution factors, calibration ranges, and quality control strategies based on sample characteristics and anticipated analyte concentrations. Assist with planning and execution of metabolomics projects to ensure timely completion of analyses. Communicate effectively with facility personnel regarding project requirements and laboratory progress.