Archean Sciences is developing autonomous brain on a chip systems that interface living neurons with advanced hardware and software. Our platform is designed to support scalable in vitro neuroscience, drug development, and biological computing by making live-cell experiments more automated, reproducible, and data-rich.

We are looking for a versatile Mechatronics / System Engineer to help build, integrate, and harden the next generation of our autonomous systems. This role will own the end-to-end physical integration of the biological interface hardware into a reliable autonomous platform.

This is a foundational engineering role for someone with high curiosity, strong technical ownership, and excitement about building paradigm-shifting systems. The ideal candidate enjoys building, debugging, and improving complex systems across hardware, software, and robotics, under biological constraints.

Responsibilities

• Build and integrate electromechanical systems, including robotics, motion control, sensors, actuators, fluid handling, and control software.

• Reproduce and improve the current system from existing documentation, including design notes, papers, and patent filings.

• Prototype rapidly across fixtures, wiring, PCB bring-up, mechanical interfaces, and system-level assemblies.

• Convert experimental and biological requirements into concrete subsystem specifications, test plans, and operating procedures.

• Design for live-cell constraints, including stable environmental control, sterile fluid handling, optical access, and electrical access.

• Develop calibration routines, diagnostics, logging infrastructure, and reliability tests.

• Harden prototypes into repeatable systems that can run defined routines with minimal supervision.

• Work closely with team members to translate scientific requirements into robust engineering execution.

What You Will Build

• An integrated autonomous bioinfrastructure platform capable of reliably running defined experimental routines.

• Build, calibration, and operating SOPs that allow the system to be reproduced and maintained.

• Reliability metrics and test infrastructure to track QC metrics, failure modes, and system performance.

• Practical engineering and industrial design improvements that move the system from working prototype toward scalable product.

Ideal Background

• Mechatronics, robotics, mechanical engineering, electrical engineering, or related fields.

• Motion control, sensors, actuators, embedded systems, FPGAs, or automation.

• Python, control software, data logging, diagnostics, or hardware-in-the-loop testing.

• PCB bring-up, wiring, fixtures, rapid prototyping, or lab instrumentation.

• Fluidics, sterile systems, environmental control, microscopy, electrophysiology, or biological instrumentation.

• Experience building systems that must operate reliably over long periods with limited supervision.

Who You Are

• A hands-on builder who enjoys making complex systems work in the real world.

• Highly curious and interested in understanding full systems, not just individual components.

• Excited by the opportunity to build paradigm-shifting technologies.

• Comfortable working across mechanical, electrical, software, and experimental domains.

• Able to prototype quickly and then refine systems to be reliable and repeatable.

• Detail-oriented with pride in clean builds and well-documented systems.

Why Join Archean

• Work on autonomous biological hardware at the intersection of robotics, neuroscience, drug development, and biological computing.

• Join early to shape platform architecture, engineering culture, and product direction.

• Build systems that move from prototype to deployed scientific infrastructure.

We Encourage You to Apply

We know that strong candidates may come from many different backgrounds. If you are excited about this role, enjoy hands-on systems building, and believe you could contribute to Archean’s mission, we encourage you to apply.

Compensation

Compensation will be competitive and commensurate with experience, with potential for equity participation as appropriate for an early-stage startup role.

Equal Opportunity

Archean Sciences is an equal opportunity employer. We consider applicants without regard to race, color, religion, sex, pregnancy, sexual orientation, gender identity, national origin, age, disability, genetic information, veteran status, or any other protected status.

To Apply

Send a resume and brief note to careers@archean.bio